Our experience with specific immune-related criteria includes studies in various phases of development (pre-clinical through phase 3) in multiple indications. BioTel Research scientists were involved in the early phases of the design of these criteria, having presented on the development of the irRECIST/iRECIST criteria at numerous industry and scientific meetings beginning in 2015.

The majority of these studies employ a dual reader with adjudication read paradigm, utilizing both in-house and contracted readers. BTR currently has software implementations of all major immune-related oncology response criteria active within the company core laboratory, including irRC, irRECIST, and iRECIST. Our flexibility and in-house scientific expertise have allowed us to implement these criteria both as published and with sponsor-specific modifications.