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Apr 21, 2012 | Jianhui Zhonga, Hongyan Nia, Tong Zhua, Sven Ekholma, Voyko Kavcicb

MR Diffusion Tensor Imaging (DTI) and Neuropsychological Testing for Neuronal Connectivity in Alzheimer’s Disease (AD) Patients

Alzheimer’s disease (AD), a neurodegenerative disorder associated with progressive functional decline, is initially diagnosed as a memory disorder accompanied by attentional and perceptual deficits. The perceptual deficits associated with AD include impaired visual motion processing with elevated thresholds for optic flow – the patterned visual motion seen during an observer self-movement.

A study was conducted to validate diffusion tensor imaging (DTI) as a new diagnostic tool for early AD.

Download the publication to discover:

  • The initial findings obtained with DTI in AD patients and age-matched controls, for the corpus callosum alone
  • How the integrity of white matter correlates with performance on some neuropsychological tests